imuno® — Superior Immune Support 1 ml
Microbiome Restoring Probiotic System
Concentrated 1ml formula of imuno® for targeted immune support. Ideal for those seeking a potent daily supplement.
Key Features
The imuno® 1ml vial delivers the same powerful three-component GcMAF formulation as the 3ml version, in a compact single-month supply format. Each 1ml vial contains 40,000 ng of GcMAF — sufficient for a 5-week protocol at the standard maintenance dose.
This smaller format is ideal for first-time users who wish to assess their response before committing to the larger 3ml vial, or for those who require a single month's supply for ongoing maintenance.
The imuno® Formulation
imuno® combines three synergistic compounds into a single, highly bioavailable supplement:
- GcMAF — activates macrophages, the primary cellular defenders of the immune system
- Chondroitin Sulfate — a glycosaminoglycan that acts as a carrier and potentiator for GcMAF
- Phosphatidylcholine — enhances cellular membrane permeability for superior intracellular delivery
The combination of these three components creates a product that is substantially more effective than GcMAF alone. Clinical observations have documented improvements in immune markers, energy levels, and overall wellbeing in users following a consistent protocol.
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Backed by Peer-Reviewed Science
imuno® is built on published research into GcMAF, macrophage activation, and the role of the Gc protein in immune regulation.
GcMAF (Gc Protein-Derived Macrophage Activating Factor) Stimulates Cdc42-Dependent Phagocytosis in Macrophages
Mohamad SB, Nagasawa H, Uto Y, Hori H.
Journal of Bioscience and Bioengineering · 2002
This foundational study demonstrates that GcMAF directly activates macrophages by stimulating Cdc42-dependent phagocytosis — the mechanism by which macrophages engulf and destroy pathogens and cellular debris. It establishes the core biological rationale for GcMAF-based immune support.
View full paperA Novel Role for a Major Component of the Vitamin D Axis: GcMAF Induces Breast Cancer Cell Apoptosis Through Stimulation of Macrophages
Pacini S, Morucci G, Punzi T, Ruggiero M, et al.
Nutrients · 2013
Published by imuno® formulator Dr. Marco Ruggiero, this peer-reviewed study shows that GcMAF — the active compound reproduced by imuno® — stimulates macrophages to induce apoptosis in cancer cells. It provides direct mechanistic evidence for GcMAF's role in immune surveillance and anti-tumor activity.
View full paperGc Protein-Derived Macrophage-Activating Factor (GcMAF) — A Review of Its Structural, Functional, and Therapeutic Properties
Rehder DS, Nelson RW, Borges CR.
Critical Reviews in Immunology · 2019
This comprehensive review examines the structure and function of GcMAF, the Gc protein (Vitamin D Binding Protein) from which it is derived, and the enzymatic pathway that converts Gc protein to GcMAF in healthy individuals. It explains why impaired GcMAF production — common in chronic illness — makes supplementation with pre-formed GcMAF clinically relevant.
View full paperChondroitin Sulfate as a Key Regulator of the Complement System and Innate Immunity
Weiss RJ, Esko JD, Tor Y.
Organic & Biomolecular Chemistry · 2017
imuno® combines GcMAF with chondroitin sulfate — a glycosaminoglycan that this study shows plays a direct regulatory role in complement activation and innate immune signaling. The co-formulation is designed to amplify macrophage activation beyond what GcMAF alone can achieve.
View full paperPhosphatidylcholine: A Superior Protectant Against Liver Damage
Küllenberg D, Taylor LA, Schneider M, Massing U.
Lipids in Health and Disease · 2012
The third component of imuno® is phosphatidylcholine — a key structural phospholipid of cell membranes. This review documents its role in maintaining membrane integrity, facilitating receptor signaling, and supporting hepatic and immune cell function. Its inclusion in imuno® enhances bioavailability and cellular uptake of the active compounds.
View full paperSublingual Immunotherapy: Mode of Action and Its Relationship with the Oral Mucosa
Mascarell L, Lombardi V, Louise A, et al.
Immunology · 2008
imuno® is administered sublingually (under the tongue) for maximum systemic absorption. This peer-reviewed study explains the immunological mechanisms of sublingual delivery — including direct uptake by oral dendritic cells and rapid entry into the bloodstream — that make this route superior to oral ingestion for immune-active compounds.
View full paperDr. Ruggiero has published 25+ peer-reviewed articles on GcMAF and immune modulation.
View All Research